产品货号：
Z20620
中文名称：
MRE11抗体
英文名称：
Anti-MRE11 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MRE11 Antibody |
| 指标别名 | ATLD;HNGS1;MRE11;MRE11 homolog 1;MRE11 homolog A;MRE11A;MRE11B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | MRE11 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MRE11 recombinant protein (Position:K14-T481). |
| 实际分子量 | 81KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene.This gene encodes a nuclear protein involved in homologous recombination,telomere length maintenance,and DNA double-strand break repair.By itself,the protein has 3' to 5' exonuclease activity and endonuclease activity.The protein forms a complex with the RAD50 homolog;this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities.In conjunction with a DNA ligase,this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments.This gene has a pseudogene on chromosome 3.Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| Uniprot ID | P49959 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | MRE11 homolog,double strand break repair nuclease |
| 蛋白名全称 | Double-strand break repair protein MRE11 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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